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In his opinion, contraindications for use of these drugs include age of less than 18 years, pregnancy or nursing, alcoholism, concomitant use of MAO inhibitors, personal or family history of pulmonary hypertension, glaucoma, untreated moderate to severe hypertension, coronary artery disease, peripheral vascular disease, seizure disorder, hyperthyroidism, and severe renal or liver disease. Adipex online order p so phentermine works by facilitating dopamine and norepinephrine release, while sibutramine facilitates serotonin release and norepinephrine release. It starts working once taken along with meals, by suppressing our appetite, reducing the lust for eating fatty food and hence increasing our metabolic rate.

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